NANCY aims to introduce a secure and intelligent architecture for the beyond the fifth-generation (B5G) wireless network. Leveraging AI and blockchain, NANCY enables secure and intelligent resource management, flexible networking, and orchestration. In this direction, novel architectures, namely point-to-point (P2P) connectivity for device-to-device connectivity, mesh networking, and relay-based communications, as well as protocols for medium access, mobility management, and resource allocation will be designed. These architectures and protocols will make the most by jointly optimizing the midhaul, and fronthaul. This is expected to enable truly distributed intelligence and transform the network into a low-power computer. By following a holistic optimization approach and leveraging the developments in blockchain, NANCY aims to support E2E personalized, multi-tenant and perpetual protection.